Dr. Madhuri Shimpi Mahajan
Department of Nuclear Medicine
MBBS, DRM, DNB Nuclear Medicine & PET-CT

Profile

Dr.Madhuri’s brings a rich experience of over 13 years. In past she worked with esteemed post graduate teaching and corporate organisations.

She has gained extensive experience in the speciality of  Nuclear Medicine with expertise across wide spectrum of various Nuclear Medicine services including PET-CT imaging, PET-CT guided applications in Oncology and benign conditions  like aortoarteritis , infections, fever of unknown origin, therapeutic radionuclide applications including thyroid disorders, neuroendocrine tumors, bone pain palliation, radiation synovectomy, radioembolisation procedures for hepatocellular cancer and liver metastasis.

She was a part of a team which started pre-therapy diagnostic somatostatin receptor scan imaging with isotope Lutetium at P.D.Hinduja national Hospital, and subsequently it was studied at various nuclear medicine centres across India. After training in the radiolabelled peptide receptor therapy at “Royal Liverpool University Hospital”, Liverpool, UK, in 2009, she was instrumental in setting up this cancer therapy in the private sector as a part of Hinduja Hospital activity.

She qualified the Radiation Safety Officer Examination in 2007, conducted by Atomic Energy Regulatory Board (AERB), Bhaba Atomic research Centre (BARC), Mumbai, India.

She has excellent knowledge in every aspect of low dose radioactive iodine treatment planning from pre-treatment assessment, making treatment management decisions, post treatment evaluation and further management.

She is well versed in handling the Isolation Ward Facility for High Dose Radio-active Iodine (131I) Therapy and other radio-nuclides for the patients of Thyroid Carcinoma, metastatic bone pain palliation, radiation synovectomy & various Neuro-Endocrine malignancies.

She has also worked on Yttrium theraspheres and SIR Spheres for Liver neoplasm.

She has in-depth knowledge of radiation precaution and radiation safety related to various diagnostic and therapeutic procedures.

She has tremendous experience in Sentinel node imaging and detection in breast and head & neck cancer patients.

She is actively involved in training Program of postgraduate courses conducted at various hospitals where she has worked.This includes delivering lectures, conducting seminars, joint clinics and appropriately teaching the students and guide them for their thesis/ dissertation. She has conducted various academic programs like CMEs, and journal clubs at regional level.

 

Area Of Interest

    ·        PET-CT imaging in Oncology (18-F FDG, 18-F Fluoride, Ga-68 PSMA, Ga-68 DOTA PET-CT scans)

    ·        PET-CT and Nuclear Neurology

    ·        PET-CT in Infections, PUO,  Aortoarteritis / Takayasu arteritis,

    ·        Nuclear Cardiology and FDG PET for Myocardial Viability

    ·        Radioactive iodine therapy (I-131 therapy) for hyperthyroidism

    ·        Radioembolisation therapy : SIRT / Theraspheres for hepatocellular cancer and liver metastasis from colorectal cancer

    ·        Bone pain palliation therapy and radiation synovectomy

    ·        Lu-177 peptide thera

Awards and Recognition

    Topper of PG entrance held for Nuclear Medicine faculty by Christian Medical College in year 2008 
    Topper of examination conducted by Bhabha Atomic Research centre in April 2005 for course of diploma in radiation medicine. 
    Topper of radiation safety officer examinations held in 2007.
    Distinction in Biochemistry.
    Chess winner for consecutive 4 years during MBBS
     

Research Publications

    • An Unusual Appearance of Meckel's Diverticulum as a Site of Bleed on Gastrointestinal Bleeding Scan MadhuriShimpiMahajan 1 World J Nucl Med. 2013 Sep;12(3):111-5

    • Technetium-99m-methylene Diphosphonate Uptake in Hepatic Necrosis Secondary to Respiratory Failure MadhuriShimpiMahajan, Negi S. Digamber, and Rajkumar Sharma World J Nucl Med. 2013 Sep-Dec; 12(3): 116-119.

    • Bone Scanning in the Adductor Insertion Avulsion Syndrome MadhuriShimpiMahajan World J Nucl Med. 2013 May-Aug; 12(2): 73-75.

    • Incidental diagnosis of primary intrathoracicgoiter on radionuclide 99m-tc pertechnetate radioisotope thyroid scan MadhuriShimpiMahajan, Digamber S Negi, Rajkumar Sharma Thyroid Research and Practice 2012 9(3):96-98

    • Primary IntrathoracicGoiter: Incidental Diagnosis On 99m-Tc Pertechnetate Radioisotope Thyroid Scan: MadhuriShimpiMahajan, Digamber S Negi , Letter to the editor- Indian Journal of Endocrinology and Metabolism / Nov-Dec 2012 / Vol 16 | Issue 6

    • Thigh splints presenting as groin pain: A case with whole body bone scan findings MadhuriShimpiMahajan, Negi S. Digamber, and Rajkumar Sharma, Saudi Journal of Sports Medicine 01/ 2013; 13(1):42.

    • Multiple brown tumors: Unusual presentation of parathyroid carcinoma , Madhuri Shimpi Mahajan, Negi S Digamber, Rajkumar Sharma, West African Journal of Radiology Vol. 19, Issue 1, January-December 2012, Page : 30-33

    • Unusual Visceral distribution of Tc-99m-MDP in a case of hypercalcemia of malignancy, MadhuriShimpiMahajan, Natasha Singh, Nitin Gupta, Indian Journal of Nuclear Medicine | Vol. 31: Issue 1 | January-March, 2016, page 67-68).

    • Incidental finding of sternal cleft on Tc99m-MDP bone scan appearing as a Necklace , MadhuriShimpimahajan, Sudeshnamaitra, Natasha Singh (Indian journal of Nuclear Medicine - letter to the editor, Year : 2016 Volume : 31, Issue : 4 | Page : 315-317

    • Diet induced high PPV of 18FDG WBPET-CT scan in prosthetic valve infection (ANMPI site, case of the month - April 2016, MadhuriShimpiMahajan, Natasha Singh)

    • IgG4 related disease simulating Paraneoplastic syndrome- Role of 18FDG PET-CT imaging MadhuriShimpiMahajan, Sudeshnamaitra, Natasha Singh (Indian Journal of Radiology and Imaging / Volume 27 / Issue 2 / April - June 2017, 249-253)

    • KCl infusion as the cause of altered bio distribution of 18F-FDG on whole body PET-CT scan, MadhuriShimpiMahajan, Natasha Singh, Sudeshna Maitra (World Journal of Nuclear Medicine/Vol 16/Issue 1/January-March 2017, 81-83)

    • Evaluation of spiritual transformation by fMRI, SPECT & psychometric analysis in healthy vegetarian males - A pilot study ( investigator: Dr Santosh Gupta, Dr Shailendra Maheshwari, Dr Urvashi Shah, Dr Rose Dawn, Dr Natasha Singh, Dr MadhuriShimpi, Mr SarvananDevang, Ms Aishani Desai, Dr Mangesh Ghodke ( under review: IJMR_194_17)

    • Does 18F-FDG PET-CT help in correctly identifying grade of cartilaginous tumors and thereby prevent the need for biopsy (Co-guide of thesis done by DNB student Dr Mandakinitphukan in year 2013)

    • Disseminated natural killer/ t cell lymphoma(cardiac and abdomioplevic disease)- unique presentation with 18-FDG PET-CT findings, Madhuri Shimpi Mahajan, SudeshnaMaitra, Natasha Singh, (Asian Journal of Oncology / Volume 3 / Issue 1 / January-June 2017, 74-77)

    • Hypereosinophillic myosoitis- Role of 18-FDG PET-CT scan MadhuriShimpiMahajan, SudeshnaMaitra, Natasha Singh (under review- Indian Journal of Haematology and transfusion)

    • Impact of Quantitative versus qualitative analysis of lymphoscitnigraphy in lymphodema patients( under research, Madhuri Shimpi Mahajan, PeriraMelvicka, Latikakhatayat, Natasha Singh)

    • Utility of bone scintigraphy in guiding management of unilateral condylar hyperplasia by serial assessment of growth activity (Swati Rachh, MadhuriShimpiMahajan, Amit Abhyankar, Natasha Singh, under review- IJNM)

    • '99mTc- RBC blood pool imaging for hepatic hemangioma- infrequently performed procedure in nuclear medicine (Swati Rachh, MadhuriShimpiMahajan, Amit Abhyankar, Natasha Singh, under review- clinical nuclear medicine) • 'Triple phase bone scan in early detection of bilateral tibial longitudinal stress fracture in non athletic female: A case report (Perira Melvicka, Madhuri Shimpi Mahajan, Amit Abhyankar, under review- IJNM).

    • Evolving role of PET scan in colorectal cancer patients with rising CEA and negative CT scans? (European Association Of Nuclear Medicine conference, abstract- European journal of Nuclear Medicine, Oct.2009). • Nuclear Dacryoscintigraphy: Will it replace traditional SAC syringing method? (European Association Of Nuclear Medicine conference , abstract- European journal of Nuclear Medicine, Oct.2009).

    • 99m-TcDMSA scan: Is it clinically relevant in negative routine urine test? (European Association Of Nuclear Medicine conference , abstractEuropean journal of Nuclear Medicine, Oct.2009).

    • Are Myocardial Perfusion Imaging and CT Coronary Angiography complimentary in the detection of silent myocardial ischemia in asymptomatic diabetic patients? ( European Association Of Nuclear Medicine conference , abstract- European journal of Nuclear Medicine, Oct.2009).

    • Finding NEMO ( Normally Evasive Malignant Origins): The Role of FDG PET in Unknown Primaries (Asia Osecina World Congress of Nuclear Medicine and Biology -2008 , abstract-Indian journal of Nuclear Medicine, Oct 2008)

    • Does recombinant human -TSH stimulates tumor growth (Indian thyroid society conference , abstract-Thyroid Research and Practice - June 2009)

    • Evolving role of PET/ CT in follow up of patients with ovarian malignancy ( World Molecular international conference meeting: Imaging Molecular and/ or Cellular Processes, Presentation Number 032, Sept.2009)

    • Does thallium scan increase the specificity of FDG PET-CT scan in pre and post treatment assessment of malignant tumors? (World Molecular international conference meeting , In Vivo Studies, Presentation Number 0572, Sept.2009)

    • FDG PET CT in non small cell carcinoma lung: Impact of SUV of the primary lesion on prognosis (SNM Annual Meeting, Toronto, June 2009)

    • Impact of FDG PET viability on the left ventricle ejection fraction post revascularization ( Nuclear cardiological society of India - November 2009)

    • EANM updates 2015 in Infection and inflammation imaging - Raheja Hospital (19 th December 2015)

    • Evaluating varying patterns on cholescintigraphy indicative of chronic cholecystsis, Indian Journal of Nuclear Medicine | Vol. 30: Issue 1 abstract supplement| December, 2015, page -13) ( 47 th annual conference of Society of Nuclear Medicine Conference 26-28 February, 2016 at JIPMER, Pondicherry, received award for best oral presentation in hepatobilliary section)

    • Cortical transit time -Can it be a sole parameter to predict the need for surgery in hydronephrosis in pediatric population? (9th european symposium on paediatric nuclear medicine( Girona, Spain, may 5-8, 2016, received award for best oral presentation)

    • Comparison of multi-time-point 99mTc sestamibi/ 99mTc pertechnetate parathyroid planar scan with conventional dual-time-point scans through interobserver agreement: A kappa analysis (Society of nuclear medicine conference 2016) • Method of 131I-thyroid uptake calculation using gamma camera system (Society of nuclear medicine conference 2016).

    • Unusual artefacts encountered during routine studies on positron emission tomographycomputed tomography and gamma camera, (Society of nuclear medicine conference 2016).

    • Impact of number of lesions analyzed for early response assessment of chemotherapy by 18F-fludeoxyglucose positron emission tomography/ computed tomography using positron emission tomography response criteria in solid tumor in carcinoma lung patients (Society Of Nuclear Medicine Conference 2016)

    • Rare sites of neurocrine tumours, The Asia Pacific Neuroendocrine Tumour Society, conference on addressing the unresolved issues in NETs-October 2017.

    • Role of nuclear medicine in GI bleed, for talk and as a panellist in the panel discussion- Prof B.Hanumaiah Memorial National Continuing surgical education program held at Bangalore medical College & research Institute from 26 th to 30th Nov. 2007.

    • Invited talk: Prosthetic joint infection imaging (Invited talk- 47 th annual conference of Society of Nuclear Medicine Conference 26-28 February, 2016 at JIPMER, Pondicherry).